TRIAMCINOLONE ACETONIDE INJECTABLE SUSPENSION USP

País: Canadá

Língua: inglês

Origem: Health Canada

Ingredientes ativos:

TRIAMCINOLONE ACETONIDE

Disponível em:

STERIMAX INC

Código ATC:

H02AB08

DCI (Denominação Comum Internacional):

TRIAMCINOLONE

Dosagem:

40MG

Forma farmacêutica:

SUSPENSION

Composição:

TRIAMCINOLONE ACETONIDE 40MG

Via de administração:

INTRA-ARTICULAR

Unidades em pacote:

1ML/5ML

Tipo de prescrição:

Prescription

Área terapêutica:

ADRENALS

Resumo do produto:

Active ingredient group (AIG) number: 0106310006; AHFS:

Status de autorização:

APPROVED

Data de autorização:

2015-09-15

Características técnicas

_Triamcinolone Acetonide Injectable Suspension USP _
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PRESCRIBING INFORMATION
PR
TRIAMCINOLONE ACETONIDE INJECTABLE
SUSPENSION USP
40 MG/ML
STERILE
CORTICOSTEROID
SteriMax Inc
Date of Revision:
2770 Portland Drive
June 08, 2022
Oakville, ON, L6H 6R4
Canada
Control Number: 261894
_Triamcinolone Acetonide Injectable Suspension USP _
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PR
TRIAMCINOLONE ACETONIDE INJECTABLE SUSPENSION USP
40 MG/ML
THERAPEUTIC CLASSIFICATION
Corticosteroid
NOTE:
Triamcinolone
Acetonide
Injectable
Suspension
USP (triamcinolone
acetonide)
is
a
synthetic glucocorticoid
corticosteroid with marked anti-inflammatory
action, in a sterile aqueous
suspension suitable for intramuscular, intra-articular, and
intrabursal injection. THIS FORMULATION
IS NOT SUITABLE FOR INTRAVENOUS, INTRADERMAL, INTRAOCULAR, EPIDURAL OR
INTRATHECAL INJECTION.
ACTION AND CLINICAL PHARMACOLOGY
Naturally
occurring
glucocorticoids
(e.g.,
hydrocortisone),
which
also
have
salt-retaining
properties, are used as replacement therapy in adrenocortical
deficiency states. Synthetic analogs
such as triamcinolone
are primarily
used for their potent anti-inflammatory
effects in disorders of
many organ systems.
Glucocorticoids
cause profound and varied metabolic effects. In addition, they modify
the body’s
immune responses to diverse stimuli.
Triamcinolone
Acetonide Injectable Suspension
USP has an extended duration of effect which
may be permanent, or sustained over a period of several weeks. Studies
indicate that following
a
single I.M. dose of 60 to 100 mg of triamcinolone acetonide, adrenal
suppression occurs within 24
to 48 hours and then gradually returns to normal, usually in 30 to 40
days. This finding correlates
closely with the extended duration of therapeutic action achieved with
the drug.
INDICATIONS AND CLINICAL USE
Intramuscular (I.M.): The I.M. administration
is indicated for systemic corticosteroid therapy in
such conditions
as dermatoses, or generalized
rheumatoid
arthritis and other connective tissue
disorders.
It
is
also
in