ACEPROMAZINE MALEATE- acepromazine maleate tablet

Țară: Statele Unite ale Americii

Limbă: engleză

Sursă: NLM (National Library of Medicine)

Ingredient activ:

ACEPROMAZINE MALEATE (UNII: 37862HP2OM) (ACEPROMAZINE - UNII:54EJ303F0R)

Disponibil de la:

Vedco, Inc.

Calea de administrare:

ORAL

Tip de prescriptie medicala:

PRESCRIPTION

Indicații terapeutice:

As an aid in tranquilization and as a preanesthetic agent in dogs. Acepromazine Maleate Tablets can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures. Phenothiazines may potentiate the toxicity of organophosphates. Therefore, do not use acepromazine maleate to control tremors associated with organic phosphate poisoning. Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars. Do not use with procaine hydrochloride.

Rezumat produs:

Acepromazine Maleate Tablets are available in 10 and 25 mg quarter-scored tablets and are supplied in bottles containing 100 and 500 tablets. NDC 50989-206-51 – 10 mg – 100 tablets NDC 50989-206-52 – 10 mg – 500 tablets NDC 50989-207-51 – 25 mg – 100 tablets NDC 50989-207-52 – 25 mg – 500 tablets

Statutul autorizaţiei:

New Animal Drug Application

Caracteristicilor produsului

ACEPROMAZINE MALEATE- ACEPROMAZINE MALEATE TABLET
VEDCO, INC.
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ACEPROMAZINE MALEATE TABLETS, USP 25 MG
NADA 117-532, Approved by FDA
For use in dogs only.
CAUTION
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DES CRIPTION
Acepromazine maleate, a potent neuroleptic agent with a low order of
toxicity, is of particular value in
the tranquilization of dogs. Its rapid action and lack of hypnotic
effect are added advantages.
CHEMIS TRY
2-acetyl-10-(3-dimethylaminopropyl) phenothiazine hydrogen maleate.
MODE OF ACTION
Acepromazine maleate has a depressant effect on the central nervous
system and therefore causes
sedation, muscular relaxation and a reduction in spontaneous activity.
It acts rapidly, exerting a prompt
and pronounced calming effect. It is an effective preanesthetic agent
and lowers the dosage requirement
of general anesthetics.
INDICATIONS
As an aid in tranquilization and as a preanesthetic agent in dogs.
Acepromazine Maleate Tablets can be
used as an aid in controlling intractable animals during examination,
treatment, grooming, x-ray and minor
surgical procedures.
DOSAGE AND ADMINISTRATION
Dogs: 0.25 - 1.0 mg/lb of body weight. Dosage may be repeated as
required.
ANIMAL SAFETY
Acute and chronic toxicity studies have shown a very low order of
toxicity for acepromazine maleate.
A safety study using elevated dosages of acepromazine maleate
demonstrated no adverse reactions even
when administered at three times the upper limit of the recommended
daily dosage (3.0 mg/lb body
weight). The clinical observation for this high dosage was mild
depression which disappeared in most
dogs 24 hours after termination of dosing.
The only occurrence of adverse reaction during numerous clinical
trials was a very mild respiratory
distress (reverse sneeze) which was transient in nature and had no
effect on the desired action of the
drug.
CONTRAINDICATIONS
Phenothiazines may potentiate the toxicity of organophosphates.
Therefore, do not use acepromazine
maleate to control tremo