CEFAZOLIN- cefazolin injection, powder, for solution

Țară: Statele Unite ale Americii

Limbă: engleză

Sursă: NLM (National Library of Medicine)

Ingredient activ:

CEFAZOLIN SODIUM (UNII: P380M0454Z) (CEFAZOLIN - UNII:IHS69L0Y4T)

Disponibil de la:

Cardinal Health

INN (nume internaţional):

CEFAZOLIN SODIUM

Compoziție:

CEFAZOLIN 1 g in 3 mL

Calea de administrare:

INTRAMUSCULAR

Tip de prescriptie medicala:

PRESCRIPTION DRUG

Indicații terapeutice:

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefazolin for Injection, USP and other antibacterial drugs, Cefazolin for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Cefazolin for Injection, USP is indicated for the treatment of the following infections when caused by susceptible bacteria. Respiratory tract infections due to Streptococcus pneumoniae , Staphylococcus aureus and Streptococcus pyogenes . Injectable benzathine penicillin is considered the drug of choice in treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever. Cefazolin is effective in the eradication of str

Rezumat produs:

Cefazolin for injection, USP Each vial contains cefazolin sodium equivalent to 1 gram of cefazolin.  Cefazolin for injection is available as follows: 1 g vials – Overbagged with 5 vials per bag, NDC 55154-7826-5 As with other cephalosporins, cefazolin tends to darken depending on storage conditions; within the stated recommendations, however, product potency is not adversely affected. Before reconstitution protect from light and store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature].

Statutul autorizaţiei:

Abbreviated New Drug Application

Caracteristicilor produsului

CEFAZOLIN- CEFAZOLIN INJECTION, POWDER, FOR SOLUTION
CARDINAL HEALTH
----------
HIGHLIGHTS OF PRESCRIBING INFORMATION
THESE HIGHLIGHTS DO NOT INCLUDE ALL THE INFORMATION NEEDED TO USE
CEFAZOLIN FOR INJECTION, USP SAFELY
AND EFFECTIVELY. SEE FULL PRESCRIBING INFORMATION FOR CEFAZOLIN FOR
INJECTION, USP.
CEFAZOLIN FOR INJECTION, USP, FOR INTRAVENOUS USE
INITIAL U.S. APPROVAL: 1973
TO REDUCE THE DEVELOPMENT OF DRUG-RESISTANT BACTERIA AND MAINTAIN THE
EFFECTIVENESS OF CEFAZOLIN FOR INJECTION
AND OTHER ANTIBACTERIAL DRUGS, CEFAZOLIN FOR INJECTION SHOULD BE USED
ONLY TO TREAT OR PREVENT INFECTIONS THAT
ARE PROVEN OR STRONGLY SUSPECTED TO BE CAUSED BY BACTERIA.
INDICATIONS AND USAGE
Cefazolin for Injection, USP is a cephalosporin antibacterial
indicated in the treatment of the following infections caused by
susceptible isolates of the designated microorganisms:
•
•
•
•
•
•
•
•
•
DOSAGE AND ADMINISTRATION
For intravenous or intramuscular use. (2)
*
RECOMMENDED DOSING SCHEDULE IN ADULT PATIENTS WITH CRCL GREATER THAN
OR EQUAL TO 55 ML/MIN. (2.1)
SITE AND TYPE OF INFECTION
DO SE
FREQUENCY
Moderate to severe infections
500 mg to 1 gram
every 6 to 8 hours
Mild infections caused by susceptible gram-
positive cocci
250 mg to 500 mg
every 8 hours
Acute, uncomplicated urinary tract infections
1 gram
every 12 hours
Pneumococcal pneumonia
500 mg
every 12 hours
Severe, life-threatening infections (e.g.,
endocarditis, septicemia)
1 gram to 1.5 grams
every 6 hours
Perioperative prophylaxis
1 gram to 2 grams
1/2 to 1 hour prior to start of
surge ry
500 mg to 1 gram
during surgery for lengthy
proce dure s
500 mg to 1 gram
every 6 to 8 hours for 24
hours postoperatively
DOSAGE FORMS AND STRENGTHS
•
CONTRAINDICATIONS
•
WARNINGS AND PRECAUTIONS
•
Respiratory tract infections. (1.1)
Urinary tract infections. (1.2)
Skin and skin structure infections. (1.3)
Biliary tract infections. (1.4)
Bone and joint infections. (1.5)
Genital infections. (1.6)
Septicemia. (1.7)
Endocarditis. (1.8)
Perioperative prophylaxis. (1.9)
I