Erythromycin ointment ointment

Страна: Армения

Язык: английский

Источник: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում

Активный ингредиент:

erythromycin

Доступна с:

Arpimed LLC

код АТС:

D10AF02

ИНН (Международная Имя):

erythromycin

дозировка:

10mg/g

Фармацевтическая форма:

ointment

Штук в упаковке:

aluminium tube 20g, aluminium tube 25g

Тип рецепта:

Prescription

Статус Авторизация:

Registered

Дата Авторизация:

2019-12-17

Характеристики продукта

1
SUMMARY PRODUCT CHARACTERISTIC (SPC)
ERYTHROMYCIN OINTMENT TRADE NAME – Erythromycin ointment
INTERNATIONAL NON-PROPERTY NAME
–
Erythromycin
COMPOSITION
Each gram of Erythromycin ointment contains:
_ACTIVE INGREDIENT_:_ _erythromycin - 10 mg;
_INACTIVE INGREDIENTS_:_ _liquid paraffin, propylparaben, white soft
paraffin (vaseline), ethanol 96%.
PHARMACOLOGICAL GROUP AND ATC CODE
Antibacterial for topical use; ATC code - D10AF02.
PHARMACOLOGICAL ACTION
Erythromycin 1% ointment contains the active ingredient erythromycin,
which is a type of medicine
known as a macrolide antibiotic.
Erythromycin is a macrolide antibiotic. It interferes with bacterial
protein synthesis by binding to the
50S subunit of ribosomes of sensitive organisms.
Erythromycin 1% ointment is applied to the skin to treat acne. The
erythromycin works by attacking
the bacteria associated with acne, _ Propionibacterium acnes_. This is
a common type of bacteria that
feeds on sebum produced by the sebaceous glands in the skin. Although
the mechanism of action of
Erythromycin in reducing inflammatory lesions of acne vulgaris has not
been conclusively shown, it is
presumably due to its antibiotic action on sensitive bacteria, and in
reducing follicular porphyrin
fluorescence and free fatty acid levels of skin lipids.
Erythromycin prevens these bacteria from producing proteins that are
essential to them. Without these
proteins the bacteria cannot grow, replicate and increase in numbers.
Erythromycin doesn’t directly
kill the bacteria, but leaves them unable to increase in numbers. The
remaining bacteria eventually die
or are destroyed by the immune system.
By controlling bacterial numbers, erythromycin brings the inflammation
of the sebaceous glands under
control, and allows the skin to heal.
The application of high doses, depending on the type of agent may also
exhibit bactericidal effect.
PHARMACOKINETICS
Only very small amounts of erythromycin appear to be absorbed
systemically following topical
application to the skin. Which subsequently excret