Država: Irska
Jezik: angleščina
Source: HPRA (Health Products Regulatory Authority)
Dexamethasone; Hydrochlorothiazide
Vetoquinol Ireland Limited
QC03AX01
Dexamethasone; Hydrochlorothiazide
0.25, 75.0 milligram(s)/gram
Oral powder
POM: Prescription Only Medicine as defined in relevant national legislation
Cattle, Non food-producing horses
hydrochlorothiazide, combinations
Cardiovascular
Authorised
1989-10-11
Health Products Regulatory Authority 28 August 2019 CRN00987J Page 1 of 4 SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE VETERINARY MEDICINAL PRODUCT Diurizone Powder 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Active Substances Hydrochlorothiazide 75.0 mg/g Dexamethasone 0.25 mg/g For a full list of excipients, see section 6.1 3 PHARMACEUTICAL FORM Oral powder. A fine, free-flowing powder 4 CLINICAL PARTICULARS 4.1 TARGET SPECIES Cattle Horses declared as not being intended for slaughter for human consumption 4.2 INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES _Cattle:_ Congestion and oedema of the udder Persistent oedema during lactation Pulmonary congestion and oedema Oedema of surgical wounds Oedema of allergic conditions _Horses:_ Generalised congestion and oedema Oedema of sheath Anasarca Oedema in allergic conditions 4.3 CONTRAINDICATIONS Do not use in pregnant animals. Do not use in animals with viral infections, during the viraemic phase. Do not use in animals with diabetes mellitus, congestive heart failure, chronic nephritis, osteoporosis or glaucoma. Do not use in animals with hepatic encephalopathy. Do not use in cases of severe hypokalemia. Do not use in animals with known hypersensitivity to the active ingredients. Do not use in horses for the treatment of laminitis. 4.4 SPECIAL WARNINGS FOR EACH TARGET SPECIES None. 4.5 SPECIAL PRECAUTIONS FOR USE SPECIAL PRECAUTIONS FOR USE IN ANIMALS None. Health Products Regulatory Authority 28 August 2019 CRN00987J Page 2 of 4 SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING THE VETERINARY MEDICINAL PRODUCT TO ANIMALS None. 4.6 ADVERSE REACTIONS (FREQUENCY AND SERIOUSNESS) The association Hydrochlorothiazide and Dexamethasone acetate may induce hepatic encephalopathy. Corticosteroids may delay wound healing and the immunosuppressant actions may weaken resistance to or exacerbate existing infections. In the presence of bacterial infection, anti-bacterial therapy is required when steroids are used. In the presence of viral infections, steroids may Preberite celoten dokument