Country: Јужноафричка Република
Језик: Енглески
Извор: South African Health Products Regulatory Authority (SAHPRA)
Lennon
CLOXAM SYRUP CLOXAM CAPSULES SCHEDULING STATUS: S4 PROPRIETARY NAME (and dosage form): CLOXAM SYRUP CLOXAM CAPSULES COMPOSITION: Ampicillin trihydrate and cloxacillin sodium available as: a) Capsules Gelatin capsules containing the equivalent of 250 mg ampicillin and 250 mg cloxacillin. b) Syrup Powder for preparing fruit flavoured syrup. When dispensed as directed each 5 mL contains the equivalent of 125 mg ampicillin and 125 mg cloxacillin. The powder contains 0,13% m/v of sodium benzoate as a preservative. PHARMACOLOGICAL CLASSIFICATION: A 20.1.2 Penicillins. PHARMACOLOGICAL ACTION: In the combination each active ingredient maintains its own spectrum of activity. The meningococcus, pneumococcus, gonococcus, and List. monocytogenes are sensitive in vitro to the combination. Haemophilus influenzae and the viridans group of streptococci are usually inhibited in vitro by low concentrations. This combination is stable in an acidic medium and is adequately absorbed after oral administration. Absorption of the combination is more efficient when they are taken on an empty stomach. INDICATIONS: Mixed infections where organisms are susceptible to the combination of Ampicillin and Cloxacillin. CONTRA-INDICATIONS: Ampicillin and Cloxacillin (Cloxam) are contra-indicated in patients known to be sensitive to penicillin and it should be used with caution in patients with known histories of allergy. Reduced doses may be required in patients with impaired renal function. DOSAGE AND DIRECTIONS FOR USE: The average adult dose for Cloxam is 2 to 4 g in divided doses per day. Preparation of the syrup: To make up to 100 mL syrup, add 57 mL water, invert the bottle and shake until all the powder is dispersed. Adults and children over 10 500 mL (1 x 500 mg capsule or 10 mL of 250 mg per 5 mL sy Прочитајте комплетан документ