Quốc gia: Singapore
Ngôn ngữ: Tiếng Anh
Nguồn: HSA (Health Sciences Authority)
Clarithromycin Citrate eqv Clarithromycin
GOLDPLUS UNIVERSAL PTE LTD
J01FA09
TABLET, FILM COATED, EXTENDED RELEASE
Clarithromycin Citrate eqv Clarithromycin 500mg
ORAL
Prescription Only
Ind-Swift Limited
ACTIVE
2022-05-13
1 CLARIPLUS EXTENDED RELEASE FILM-COATED TABLETS 500MG COMPOSITION: Each film coated extended-release tablet contains Clarithromycin Citrate equivalent to Clarithromycin 500mg LIST OF EXCIPIENTS: _TABLET CORE _ Lactose Monohydrate, Hydroxypropyl methylcellulose, Purified Water, Hydroxypropyl methyl cellulose phthalate, Purified Talc and Magnesium Stearate _ _ _FILM COAT _ Opadry II Yellow 31G52300 (consist of Hypromellose, Lactose Monohydrate, Titanium Dioxide, Polyethylene Glycol, Talc and Quinoline Yellow Aluminium Lake) and Purified Water PRESENTATION: Blisters composed of Rigid PVC film coated with PVdC Pharma Grade and Printed Aluminium foil. Blister packs are supplied in cartons of 7, 10, 70 or 100 tablets. PRODUCT DESCRIPTION: Yellow colored, film coated, oblong shaped, biconvex tablet, with both sides plain. PROPERTIES: Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is 6-0-methylerythromycin. The molecular formula is C 38 H 69 NO 13 , and the molecular weight is 747.96. The structural formula is O H 3 C O CH 3 CH 3 H 3 C H 3 C H 3 C HO OH OCH 3 CH 3 O O O H 3 C CH 3 O C H 3 HO O O N HO CH 3 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 22 19 20 21 1" 2" 1' 2' 3' 4' 5' 6' 3" 4" 6" 5" CH 3 CH 3 8' 7' 7" CLINICAL PHARMACOLOGY: PHARMACODYNAMICS: Pharmacotherapeutic group: Antibacterial for systemic use, macrolide ATC-Code: J01FA09 Clarithromycin is a semi-synthetic macrolide antibiotic obtained by substitution of a CH3O group for the hydroxyl (OH) group at position 6 of the erythromycin lactonic ring. Specifically clarithromycin is 6-O-methyl erythromycin A. The white to off-white antibiotic powder is bitter, practically odorless, essentially insoluble in water, and slightly soluble in ethanol, methanol, and acetonitrile. Its molecular weight is 747.96. 2 A study in community acquired pneumonia investigated the effect of clarithromycin vs amoxicillin on plasma concentrations of IL-6, IFNγ and IL-10 before starting therapy [1st day] and at the 3rd and 7th days of therapy. Twenty-three Đọc toàn bộ tài liệu
1 GP CLARITHROMYCIN X R TABLET 500MG COMPOSITION: Each film coated extended-release tablet contains Clarithromycin Citrate equivalent to Clarithromycin 500mg LIST OF EXCIPIENTS: _TABLET CORE _ Lactose Monohydrate, Hydroxypropyl methylcellulose, Purified Water, Hydroxypropyl methyl cellulose phthalate, Purified Talc and Magnesium Stearate _FILM COAT _ Opadry II Yellow 31G52300 (consist of Hypromellose, Lactose Monohydrate, Titanium Dioxide, Polyethylene Glycol, Talc and Quinoline Yellow Aluminium Lake) and Purified Water PRESENTATION: Blisters composed of Rigid PVC film coated with PVdC Pharma Grade and Printed Aluminium foil. Blister packs are supplied in cartons of 5, 7, 10, 50, 70 or 100 tablets. PRODUCT DESCRIPTION: Yellow colored, film coated, oblong shaped, biconvex tablet, with both sides plain. PROPERTIES: Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is 6-0-methylerythromycin. The molecular formula is C 38 H 69 NO 13 , and the molecular weight is 747.96. The structural formula is O H 3 C O CH 3 CH 3 H 3 C H 3 C H 3 C HO OH OCH 3 CH 3 O O O H 3 C CH 3 O C H 3 HO O O N HO CH 3 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 22 19 20 21 1" 2" 1' 2' 3' 4' 5' 6' 3" 4" 6" 5" CH 3 CH 3 8' 7' 7" CLINICAL PHARMACOLOGY: PHARMACODYNAMICS: Pharmacotherapeutic group: Antibacterial for systemic use, macrolide ATC-Code: J01FA09 Clarithromycin is a semi-synthetic macrolide antibiotic obtained by substitution of a CH3O group for the hydroxyl (OH) group at position 6 of the erythromycin lactonic ring. Specifically clarithromycin is 6-O-methyl erythromycin A. The white to off-white antibiotic powder is bitter, practically odorless, essentially insoluble in water, and slightly soluble in ethanol, methanol, and acetonitrile. Its molecular weight is 747.96. 2 A study in community acquired pneumonia investigated the effect of clarithromycin vs amoxicillin on plasma concentrations of IL-6, IFNγ and IL-10 before starting therapy [1st day] and at the 3rd and 7th days of therapy. Twenty-three patients receiv Đọc toàn bộ tài liệu