国家: 马来西亚
语言: 英文
来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Cetalkonium Chloride; Choline Salicylate
APEX PHARMACY MARKETING SDN. BHD.
Cetalkonium Chloride; Choline Salicylate
10gm mcg/mL; 50 tubes x 10g
XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ _ _ _ _ _ _ _____________________________________________________________________________________________________________________________ _ ________________________________________________________________________________________________________________ 1 WHAT IS IN THIS LEAFLET: 1. What is Avera used for 2. How Avera works 3. Before you use Avera 4. How to use Avera 5. While you are using Avera 6. Side effects 7. Storage and disposal of Avera 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT IS AVERA USED FOR Avera is used for mouth ulcers, cold sores, and during teething. It helps to relieve pain, inflammation, and to treat minor infection. HOW AVERA WORKS Avera contains non-steroidal anti- inflammatory (NSAID) and anti-infective substances. Choline Salicylate is a NSAID that reduces pain and inflammation. Cetalkonium Chloride is an anti-infective agent that fights against microbial growth. BEFORE YOU USE AVERA _When you must not to use it _ Do not use Avera if: You are allergic to Choline Salicylates, Cetalkonium Chloride, Ethanol or Glycerin. You are taking medicines for blood clots or gout. You have stomach or intestinal bleeding. You have blood clotting disorders. You are suffering from stomach ulcer. _ _ _Before you start to use it _ Tell your doctor or pharmacist if: You are pregnant or breast-feeding._ _ You have blood clotting disorders._ _ _ _ _Taking other medicines _ Tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes any medicines which you have bought without a prescription. Tell your doctor or pharmacist if you are taking medicines for treating blood clotting or gout. HOW TO USE AVERA _How much to use_ _BABIES (4 MONTH-OLD AND ABOVE) AND _ _CHILDREN _ With clean finger, massage approximately one half centimeter of AVERA gel onto the sore area. This can be repeated after 3 hours. Not to exceed 6 doses in 24 ho 阅读完整的文件
Important Information. Please read carefully. AVERA GEL WHAT IS AVERA? Description, Dosage form and Packaging AVERA is a translucent colourless gel containing Choline Salicylate 8.71%w/w and Cetalkonium Chloride 0.01%w/w. Contains Ethanol 33.46% w/w. This product is available in pack size of 10g tube. WHAT IS AVERA USED FOR? AVERA helps to relieve pain, inflammation, and to treat minor infection due to common mouth ulcers, cold sores, denture and sore spots, as well as mouth ulcers, and sore spots due to orthodontic devices. To help to fight minor mouth infection and healing of sore spots and ulcers to dentures and orthodontic devices. HOW AVERA WORKS? AVERA contains non-steroidal anti-inflammatory (NSAID) and anti-infective substances. Choline Salicylate is a NSAID that reduces pain and inflammation. Cetalkonium Chloride is an anti-infective agent that fights against microbial growth. Pharmacodynamics Choline salicylate is the choline salt of salicylic acid and its pharmacology is essentially that of salicylic acid. It has exhibited anti- inflammatory, analgesic and antipyretic actions in animal models, and is taken orally or is applied topically in man for the relief of pain and inflammation. Like salicylic acid it has no antithrombotic activity and shows a low potential for production of gastrointestinal injury when given by the oral route. The pharmacological actions of choline salicylate are thought to be primarily mediated through inhibition of prostaglandin production, although effects on leukotriene pathways, kinin release and nerve conduction have been proposed. Cetalkonium chloride is a quaternary ammonium antimicrobial agent, being bactericidal towards both Gram positive and Gram negative organisms, but with preferences for the former. Pharmacokinetics Choline salicylate is absorbed from the gut and is likely to be absorbed across mucous membrane such as all buccal mucosa. Metabolism of salicylic acid is by glycine and phenolic or acyl glucoronate conjunction with small amounts undergoing hydroxylation 阅读完整的文件