ETOMIDATE-LIPURO

国家: 以色列

语言: 英文

来源: Ministry of Health

有效成分:

ETOMIDATE

可用日期:

LAPIDOT MEDICAL IMPORT AND MARKETING LTD

ATC代码:

N01AX07

药物剂型:

EMULSION FOR INJECTION

组成:

ETOMIDATE 20 MG / 10 ML

给药途径:

I.V

处方类型:

Required

厂商:

B.BRAUN MELSUNGEN AG, GERMANY

治疗组:

ETOMIDATE

治疗领域:

ETOMIDATE

疗效迹象:

Induction of general anaesthesia.

授权日期:

2019-04-30

产品特点

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
Etomidate-Lipuro
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
1 ml of emulsion for injection contains
2 mg of etomidate
10 ml of emulsion for injection (= 1 ampoule) contain
20 mg of etomidate
Excipients with known effect:
One ampoule (10 ml) of emulsion for injection contains:
Soya-bean oil, refined
1.0 g
Sodium (as sodium oleate)
0.23 mg
For the full list of excipients, see section 6.1.
3
PHARMACEUTICAL FORM
Emulsion for injection.
Milky-white oil-in-water emulsion
pH
6.0 – 8.5
4
CLINICAL PARTICULARS
4.1
THERAPEUTIC INDICATIONS
Induction of general anaesthesia.
_ _
_Notice: _
For short-term narcosis, Etomidate-Lipuro must be combined with an
analgesic drug.
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Posology
The dosage is adjusted acc. to the individual response and the
clinical effect.
_The following dosage guidelines should be followed: _
As a rule, the effective hypnotic dose is between 0.15 and 0.3 mg of
etomidate per kg
body weight, corresponding to 0.075 to 0.15 ml of Etomidate-Lipuro per
kg body
weight.
Children up to the age of 15 and elderly patients are given a single
dose of 0.15 to 0.2
mg of etomidate, corresponding to 0.075 to 0.1 ml of Etomidate-Lipuro
per kg body
weight. Also in patients belonging to these age groups, the exact
dosage has to be
adjusted acc. to the clinical effect. In children up to the age of 15
the dosage may be
increased by up to 30 % of the adult dose because it is sometimes
necessary in order
to obtain the same depth and duration of sleep.
Since etomidate has no analgesic action, appropriate analgesics should
be used in
procedures involving painful stimuli.
Do not exceed a total dose of 30 ml (3 ampoules). Etomidate should
only be given by
slow intravenous injection.
In patients with liver cirrhosis and patients having been premedicated
with
neuroleptics opioids or sedatives the dose has to be reduced.
In the special case of narcosis to terminate a status epilepticus or
serial epileptic
seizures a sufficient d