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INDICATIONS [/za_1324.html#1]
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CONTRA-INDICATIONS [/za_1324.html#1]
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DOSAGE [/za_1324.html#1]
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SIDE-EFFECTS [/za_1324.html#1]
[/za_1324.html#1] PREGNANCY [/za_1324.html#1]
OVERDOSE [/za_1324.html#1]
IDENTIFICATION [/za_1324.html#1]
[/za_1324.html#1] PATIENT INFORMATION
INTRAMED HYDROCORTISONE SODIUM SUCCINATE
INJECTION 100 MG
INTRAMED HYDROCORTISONE SODIUM SUCCINATE
INJECTION 500 MG
SCHEDULING STATUS:
S4
PROPRIETARY NAME:
(and dosage form)
INTRAMED HYDROCORTISONE SODIUM SUCCINATE INJECTION 100 MG
INTRAMED HYDROCORTISONE SODIUM SUCCINATE INJECTION 500 MG
COMPOSITION:
100 mg
HYDROCORTISONE
as sodium succinate.
500 mg Hydrocortisone as sodium succinate.
Diluent containing 0,5% Benzyl alcohol as bacteriostat.
PHARMACOLOGICAL CLASSIFICATION:
A.21.5.1 –Corticosteroids and analogues.
A.34 –Others –Diluent
PHARMACOLOGICAL ACTION:
Hydrocortisone sodium succinate acts by controlling the rate of protein synthesis. It forms a steroid-receptor complex
with receptor proteins, moves into the nucleus where it binds the chromatin and thus directs the genetic apparatus to
transcribe RNA. It also delays the mineralocorticoid activity.
INDICATIONS:
As substitution therapy in the treatment of adrenal insufficiency states, where high levels of hydrocortisone are required
rapidly.
In patients with known or suspected adrenal insufficiency prior to surgery, or if shock, severe trauma or other stress
conditions occur.
Hydrocortisone sodium succinate is also used for the symptomatic relief of inflammatory conditions and as an
immunosuppressant.
CONTRA-INDICATIONS:
Hypersensitivity to corticosteroids. Tuberculosis. Ocular herpes simplex. Primary glaucoma. Acute psychosis and
psychoneurosis. Systemic infection. Peptic ulcer. Osteoporosis.
W
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