IVERMECTIN POUR-ON FOR CATTLE- ivermectin solution

国家: 美国

语言: 英文

来源: NLM (National Library of Medicine)

有效成分:

ivermectin (UNII: 8883YP2R6D) (ivermectin - UNII:8883YP2R6D)

可用日期:

Durvet, Inc.

INN（国际名称）:

ivermectin

组成:

ivermectin 5 mg in 1 mL

给药途径:

TOPICAL

处方类型:

OTC

疗效迹象:

Ivermectin Pour-On (ivermectin topical solution) applied at the recommended dose level of 500 mcg/kg is indicated for the effective control of these parasites. Gastrointestinal Roundworms Mites Sarcoptes scabiei var. bovis Lice Linognathus vituli Haematopinus eurysternus Damalinia bovis Solenopotes capillatus Horn Flies Haematobia irritans

產品總結:

Ivermectin Pour-On (ivermectin topical solution) is available in a 33.8 fl oz/1L bottle with a measure-squeeze-pour-system or in an 84.5 fl oz/2.5 L or 169 oz/5 L collapsible pack, or 676 fl oz/20 L container intended for use with appropriate automatic dosing equipment. Restricted Drug - California. Use Only as Directed. Approved by FDA under ANADA # 200-272 Manufactured for: DURVET, INC. Blue Springs, Missouri 64014 www.durvet.com Rev. 03/20 009215I04

授权状态:

Abbreviated New Animal Drug Application

产品特点

IVERMECTIN POUR-ON FOR CATTLE - IVERMECTIN SOLUTION
DURVET, INC.
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DURVET
IVERMECTIN POUR-ON
(IVERMECTIN TOPICAL SOLUTION)
_FOR CATTLE_
Contains 5 mg ivermectin/mL
Parasiticide
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT
AND CONTROL OF PARASITISM.
INTRODUCTION
Ivermectin Pour-On (ivermectin topical solution) delivers internal and
external parasite control in one
convenient low-volume application. Ivermectin Pour-On (ivermectin
topical solution) contains
ivermectin, a unique chemical entity.
MODE OF ACTION
Ivermectin is a member of the macrocylic lactone class of endectocides
which have a unique mode of
action. Compounds of the class bind selectively and with high affinity
to glutamate-gated chloride ion
channels which occur in invertebrate nerve and muscle cells.
This leads to an increase in the permeability of the cell membrane to
chloride ions with
hyperpolarization of the nerve or muscle cell, resulting in paralysis
and death of the parasite.
Compounds of this class may also interact with other ligand -gated
chloride channels, such as those
gated by the neurotransmitter gamma-aminobutyric acid (GABA).
The margin of safety for compounds of this class is attributable to
the fact that mammals do not have
glutamate-gated chloride channels, the macrocylic lactones have a low
affinity for other mammalian
ligand-gated chloride channels and they do not readily cross the
blood-brain barrier.
INDICATIONS
Ivermectin Pour-On (ivermectin topical solution) applied at the
recommended dose level of 500 mcg/kg
is indicated for the effective control of these parasites.
GASTROINTESTINAL ROUNDWORMS
_Ostertagia ostertagi_
(including inhibited stage)
(adults and L4)
_Haemonchus placei_
(adults and L4)
_Trichostrongylus axei_
(adults and L4)
_T. colubriformis_
(adults and L4)
_Cooperia oncophora_
(adults and L4)
_Cooperia punctata_
(adults and L4)
_Cooperia surnabada_
(adults and L4)
_Strongyloides papillosus_
(adults)
_Oesophagostomum radiatum_
(adults and L4)
_Trichuris_ spp.
(adults)
LUNGWORMS
_D