资料单张
LEN V.K. 250 mg TABLETS
LEN V.K. 500 mg TABLETS
LEN V.K. 250 SYRUP
SCHEDULING STATUS:
S4
PROPRIETARY NAME
(and dosage form):
LEN V.K. 250 mg TABLETS
LEN V.K. 500 mg TABLETS
LEN V.K. 250 SYRUP
COMPOSITION:
Each tablet contains the equivalent of 250 mg or 500 mg
Phenoxymethylpenicillin
as the potassium salt.
When dispensed as directed each 5 mL contains the equivalent of 250 mg Phenoxymethylpenicillin as the potassium salt
Preservative: Sodium Benzoate 0,1% m/v
PHARMACOLOGICAL CLASSIFICATION:
A 20.1.2 Penicillins.
PHARMACOLOGICAL ACTION:
Phenoxymethylpenicillin is a narrow spectrum penicillin, inhibited by penicillinase. It has an antimicrobial spectrum
similar to benzylpenicillin for aerobic Gram + organisms. Itis more stable in acidic medium than benzylpenicillin and is
therefore better absorbed from the gastro-intestinal tract.
Once absorbed it is widely distributed throughout the body, and normally rapidly eliminated from the body, mainly by
the kidneys.
INDICATIONS:
Prophylactic: Recurrence of rheumatic fever. Treatment of mild to moderate infections caused by sensitive organisms:
Pneumococcal infections of the middle ear; Streptococcal otitis media and sinusitis; Streptococcal pharyngitis caused by
Strep pyogenes; mild to moderate pulmonary and periodontal anaerobic infections; gingivostomatitis; early Lyme
disease.
CONTRA-INDICATIONS:
Phenoxymethylpenicillin should not be given to patients known to be allergic to penicillin and should be given with
care to patients with a history of allergy to cephalosporins. Cases of cross sensitivity have been reported. It should not be
given to babies, in the neonatal period, born of hypersensitive mothers. It is not recommended for chronic, severe or deep-
seated infections such as subacute bacterial endocarditis, meningitis or syphilis.
WARNINGS:
阅读完整的文件
资料单张 