国家: 加拿大
语言: 英文
来源: Health Canada
TULATHROMYCIN
NORBROOK LABORATORIES LTD.
100MG
SOLUTION
TULATHROMYCIN 100MG
INTRAMUSCULAR
15G/50G
Prescription
CATTLE; SWINE (PIGS); SHEEP
Active ingredient group (AIG) number: 0151667001
APPROVED
2020-12-07
Tulathromycin Injection English Insert (100ml/250ml) Dimensions: 148 mm x 210 mm Font Size: ≥ 5pt Printed at 100% DIN 02505401 TULIEVE Tulathromycin Injection VETERINARY USE ONLY Sterile - Antibiotic DESCRIPTION: Tulieve is a ready-to-use sterile parenteral preparation containing tulathromycin, a semi-synthetic macrolide antibiotic of the subclass triamilide. Each mL of Tulieve contains 100 mg of tulathromycin as the free base in a propylene glycol vehicle. Tulieve consists of an equilibrated mixture of two isomeric forms of tulathromycin in a 9:1 ratio. Structures of the isomers are shown below: Figure 1. The chemical names of isomers are (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R) -13-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo-hexopyranosyl] oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino) -β-D-xylo-hexopyranosyl]-oxy]-1-oxa-6-azacyclopentadecan-15-one and (2S, 3S, 6R, 8R, 9R, 10S, 11S,12R)-11-[[2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-[(propylamino)methyl]-α-L-ribo- hexopyranosyl]oxy]-2-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-8-hydroxy-3,6,8,10,12-pentamethyl- 9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylohexopyranosyl]-oxy]1-oxa-4-azacyclotridecan-13 -one, respectively. INDICATIONS: BEEF AND NON-LACTATING DAIRY CATTLE. BOVINE RESPIRATORY DISEASE (BRD): Tulieve is indicated for the treatment of BRD associated with _Mannheimia _ _haemolytica, _ _Pasteurella _ _multocida, _ _Histophilus _ _somni _ _(Haemophilus _ _somnus)_ and _Mycoplasma bovis_ and for the reduction of morbidity associated with BRD in feedlot calves caused by _Mannheimia haemolytica, Pasteurella multocida, Histophilus somni _and _Mycoplasma bovis, _during the first 14 days in the feedlot when administered at the time of arrival. INFECTIOUS BOVINE KERATOCONJUNCTIVITIS (IBK): Tulieve is indicated for the treatment of IBK associated with _Moraxella bovis._ FOOT ROT: Tulieve is indicated for the treatment of bovine foot rot (interdigital necrobacillosis) associated with _Fu 阅读完整的文件