Land: Australien
Sprog: engelsk
Kilde: Department of Health (Therapeutic Goods Administration)
Perindopril arginine; Amlodipine besylate
Servier Laboratories (Australia) Pty Ltd
Medicine Registered
REAPTAN ® _5MG/5MG; 5MG/10MG; 10MG/5MG; 10MG/10MG_ _Perindopril/amlodipine [pronounced per-in-do-pril/ am-load-i-peen]_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about REAPTAN. It does not contain all the available information about this medicine. Reading this leaflet does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking REAPTAN against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. YOU MAY NEED TO READ IT AGAIN. WHAT REAPTAN IS The name of your medicine is REAPTAN. The medicine contains the active ingredient perindopril arginine. Perindopril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors. It also contains the active ingredient amlodipine besylate. Amlodipine belongs to a group of medicines called calcium channel blockers. Calcium channel blockers do not change the amount of calcium in your blood or bones. REAPTAN has been prescribed for you by your doctor to replace the separate tablets of perindopril and amlodipine you were taking. One REAPTAN tablet replaces separate tablets of perindopril and amlodipine. WHAT REAPTAN IS USED FOR You have been prescribed REAPTAN if you have high blood pressure, also known as hypertension. _WHY REAPTAN IS USED FOR_ _HIGH BLOOD PRESSURE_ Everyone has blood pressure. This pressure helps get your blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or stressed you are. You have high blood pressure when your blood pressure stays higher than is needed, even when you are calm or relaxed. There are usually no symptoms of high blood pressure. The only way of knowing that you have it is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to seriou Læs hele dokumentet
REAPTAN ® (PERINDOPRIL ARGININE/AMLODIPINE BESYLATE) – PRODUCT INFORMATION 1 (28) Version 3 _ _ PRODUCT INFORMATION NAME OF THE MEDICINE _REAPTAN 5MG/5MG _ perindopril arginine 5 mg/amlodipine besylate † 5 mg _REAPTAN 5MG/10MG _ perindopril arginine 5 mg/amlodipine besylate 10 mg _REAPTAN 10MG/5MG _ perindopril arginine 10 mg/amlodipine besylate 5 mg _REAPTAN 10MG/10MG _ perindopril arginine 10 mg/amlodipine besylate 10 mg RELATED TO PERINDOPRIL CAS Registry Number_: 612548-45-5 _ _ _ _Molecular formula_: C 19 H 32 N 2 O 5 , C 6 H 14 N 4 O 2 _Chemical structure_: , N H H COOH O N H CH 3 C H 3 O O C H 3 N H 2 N H NH COOH NH 2 RELATED TO AMLODIPINE _CAS Registry Number_: 111470-99-6 _Molecular formula_: C 20 H 25 CIN 2 O 5 .C 6 H 6 O 3 S _Chemical structure_: REAPTAN ® (PERINDOPRIL ARGININE/AMLODIPINE BESYLATE) – PRODUCT INFORMATION 2 (28) Version 3 DESCRIPTION ACTIVE INGREDIENTS PERINDOPRIL ARGININE has the chemical name, L-arginine (2S, 3aS, 7aS) - 1 - N - [ (S) -1 - ethoxycarbonyl butyl ] - L - alanyl) perhydroindole-2 - carboxylate. It is a dipeptide monoacid monoester with a perhydroindole group and no sulphydryl radical. Perindopril arginine is a white powder, readily soluble in purified water, slightly soluble in 95% ethanol and practically insoluble in chloroform. Perindopril has five asymmetric centres. The drug is synthesised stereoselectively so that it is a single enantiomer (all S stereochemistry). AMLODIPINE BESYLATE is a dihydropyridine derivative, and has the following chemical name: 3-ethyl 5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5- pyridinedicarboxylate benzene Læs hele dokumentet