Land: Australien
Sprache: Englisch
Quelle: Department of Health (Therapeutic Goods Administration)
amoxicillin trihydrate,potassium clavulanate
Southern Cross Pharma Pty Ltd
amoxicillin trihydrate,potassium clavulanate
Registered
C:Products/Amoxiclav/CMI Moxi 28nov11 28/11/11 Page 1 of 8 MOXICLAV DUO 500/125 AND MOXICLAV DUO FORTE 875/125 [AMOXICILLIN TRIHYDRATE AND POTASSIUM CLAVULANATE] CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about this medicine. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you being given this medication against the benefits it is expected to have for you. If you have any concerns about being given this medicine, ask your doctor or pharmacist. Keep this leaflet. You may need to read it again. WHAT MOXICLAV DUO 500/125 AND MOXICLAV DUO FORTE 875/125 ARE USED FOR Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets contain two active ingredients. One of these is from the penicillin group of antibiotics and is called amoxicillin (from amoxicillin trihydrate) and the other is clavulanic acid (from potassium clavulanate). Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets are used to treat a wide range of infections caused by bacteria. These infections may affect the chest (bronchitis or pneumonia), bladder (cystitis), sinuses (sinusitis), the ears (otitis media) or the skin. Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets work by killing the bacteria that cause these infections. Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets will not work against infections caused by viruses such as colds or the flu. Your doctor may prescribe Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets for another use. If you want more information ask your doctor. There is no evidence that Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets are addictive. BEFORE TAKING MOXICLAV DUO 500/125 AND MOXICLAV DUO FORTE 875/125 FOR THE FIRST TIME _Do not take Moxiclav Duo 500/125 and Moxiclav Duo Forte 875/125 tablets if: _ _ _ C:Products/Amoxiclav/CMI Moxi 28nov11 28/11/11 Page 2 of 8 you hav Lesen Sie das vollständige Dokument
C:Products/Amoxiclav/PI Moxiclav_14012013_2 Page 1 of 17 PRODUCT INFORMATION MOXICLAV DUO 500/125 AND MOXICLAV DUO FORTE 875/125 NAME OF THE MEDICINE PROPRIETARY NAMES: MOXICLAV DUO 500/125 tablets; and MOXICLAV DUO FORTE 875/125 tablets NON PROPRIETARY NAME: Co-amoxiclav tablets CHEMICAL NAMES:_ _ Amoxicillin trihydrate: (2 _S_ ,5 _R_ ,6 _R_ )-6-[( _R_ )-(-)-2-Amino-2-( _p_ –hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate. Potassium clavulanate: Potassium ( _Z_ )-(2 _R_ ,5 _R_ )-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]-heptane-2- carboxylate. MOLECULAR FORMULA AND MOLECULAR WEIGHT: Amoxicillin trihydrate – the molecular formula is C 16 H 19 N 3 O 5 S ּ ◌3H 2 O, and the molecular weight is 419.46. Potassium clavulanate – the molecular formula is C 8 H 8 KNO 5 , and the molecular weight is 237.25. STRUCTURES: _ _ The chemical structure of amoxicillin trihydrate is: C:Products/Amoxiclav/PI Moxiclav_14012013_2 Page 2 of 17 The chemical structure of potassium clavulanate is: CAS NUMBERS: Amoxicillin trihydrate - 61336-70-7, and Potassium clavulanate - 61177-45-5 _ _ DESCRIPTION Amoxicillin is a semi-synthetic antibiotic. Amoxicillin trihydrate is a white to off white crystalline powder and is slightly soluble in water. Clavulanic acid is an irreversible inhibitor of many beta-lactamase enzymes except type 1 (Richmond). It is a beta-lactam compound with only weak antibacterial activity in its own right. Potassium clavulanate is a white to off white hygroscopic crystalline powder and is freely soluble in water. Moxiclav Duo 500/125 is an immediate release tablet form and each tablet contains amoxycillin trihydrate equivalent to 500 mg amoxicillin and potassium clavulanate equivalent to 125 mg clavulanic acid. Moxiclav Duo Forte 875/125 is an immediate release tablet form and each tablet contains amoxycillin trihydrate equivalent to 875 mg amoxicillin and potassium clavulanate equivalent to 125 mg clavulanic acid. _ _ The excipients cont Lesen Sie das vollständige Dokument