AMPICILLIN SODIUM- ampicillin sodium injection, powder, for solution

País: Estados Unidos

Idioma: inglés

Fuente: NLM (National Library of Medicine)

Ingredientes activos:

AMPICILLIN SODIUM (UNII: JFN36L5S8K) (AMPICILLIN - UNII:7C782967RD)

Disponible desde:

GC Hanford Manufacturing Company

Designación común internacional (DCI):

AMPICILLIN SODIUM

Composición:

AMPICILLIN 1 g

Vía de administración:

INTRAVENOUS

tipo de receta:

PRESCRIPTION

indicaciones terapéuticas:

Ampicillin sodium is indicated in the treatment of susceptible strains of the organisms causing the following infections in the horse: Respiratory tract infections (pneumonia and strangles) due to Staphylococcus spp., Streptococcus spp. (including S. equi ), E. coli, and Proteus mirabilis . Skin and soft tissue infections (abscesses and wounds) due to Staphylococcus spp., Streptococcus spp., E. coli , and Proteus mirabilis. As with all antibiotics, appropriate in vitro culturing and susceptibility testing of samples taken before treatment should be conducted. The use of this drug is contraindicated in animals with a history of an allergic reaction to penicillin.

Resumen del producto:

Ampicillin Sodium is supplied in vials containing 1 gram and 3 grams of ampicillin activity. Store dry powder at room temperature, 15° to 30°C (59° to 86°F). NDC 10515-335-01                   1 gm vial NDC 10515-335-03                   3 gm vial ANADA 200-335       Approved by FDA Manufactured by: G.C. Hanford Mfg. Co. Syracuse, NY 13201                   INS15793 03           7/2011

Estado de Autorización:

Abbreviated New Animal Drug Application

Ficha técnica

AMPICILLIN SODIUM- AMPICILLIN SODIUM INJECTION, POWDER, FOR SOLUTION
GC HANFORD MANUFACTURING COMPANY
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AMPICILLIN SODIUM
FOR INTRAVENOUS OR INTRAMUSCULAR USE IN HORSES ONLY
DESCRIPTION
Ampicillin sodium is a semisynthetic penicillin with a broad spectrum
of activity. Ampicillin is derived
from the penicillin nucleus, 6-aminopenicillanic acid (6 APA).
Chemically it is D(-)α-aminobenzyl
penicillin sodium salt.
ACTION
Ampicillin sodium provides bactericidal activity against a wide range
of common Gram-positive and
Gram-negative pathogens. Ampicillin’s activity occurs during the
stage of active multiplication of the
pathogen and acts through inhibition of biosynthesis of cell wall
mucopeptide. _In vivo _studies have
demonstrated the susceptibility of many strains of the following
Gram-positive bacteria: _Staphylococcus_
spp. and_ Streptococcus_ spp. (including _S. equi_). _In vivo_ studies
have also demonstrated the susceptibility
of many strains of the following Gram-negative bacteria:_ E. coli_ and
_Proteus mirabilis_. Because it does
not resist destruction by penicillinase, it is not effective against
penicillinase-producing bacteria,
particularly resistant staphylococci. Most strains of Pseudomonas,
Klebsiella and Aerobacter are
resistant.
Ampicillin sodium diffuses readily into all body tissues and fluids,
with the exception of brain and
spinal fluid except when the meninges are inflamed. It produces high
and persistent blood levels. Most
of the ampicillin is excreted unchanged in the urine.
INDICATIONS
Ampicillin sodium is indicated in the treatment of susceptible strains
of the organisms causing the
following infections in the horse: Respiratory tract infections
(pneumonia and strangles) due to
_Staphylococcus_ spp., _Streptococcus _spp. (including _S. equi_), _E.
coli,_ and _Proteus mirabilis_.
Skin and soft tissue infections (abscesses and wounds) due to
_Staphylococcus _spp., _Streptococcus_ spp., _E._
_coli_, and _Proteus mirabilis._
As with all antibiotics, appropriate in vitroculturing and
s