ATENOLOL GH atenolol 50 mg tablets blister pack

מדינה: אוסטרליה

שפה: אנגלית

מקור: Department of Health (Therapeutic Goods Administration)

מרכיב פעיל:

atenolol

זמין מ:

Generic Health Pty Ltd

INN (שם בינלאומי):

Atenolol

מצב אישור:

Registered

עלון מידע

Atenolol GH CMI v3 Aug17
Page 1 of 6
CONSUMER MEDICINE INFORMATION
ATENOLOL GH
atenolol
What is in this leaflet
This leaflet answers some
common questions about
Atenolol GH. It does not
contain all the available
information. It does not take
the place of talking to your
doctor or pharmacist.
All medicines have benefits
and risks. Your doctor has
weighed the risks of you
taking Atenolol GH against
the benefits they expect it will
have for you.
This medicine may also be
used in emergency situations
where you may be
unconscious. In this case,
this leaflet may be given to
you after the medicine has
been used.
If you have any concerns
about taking this medicine,
ask your doctor or
pharmacist.
Keep this leaflet with the
medicine. You may need to
read it again.
What Atenolol GH is
used for
Atenolol GH belongs to a
group of medicines called
beta-blockers. It works by
affecting the body's response
to certain nerve impulses,
especially in the heart. As a
result, it decreases the
heart's need for blood and
oxygen and therefore
reduces the amount of work
the heart has to do. It widens
the blood vessels in the body,
causing blood pressure to
fall. It also helps the heart to
beat more regularly.
Atenolol GH is used to:

lower high blood
pressure, which is called
hypertension

prevent angina

treat irregular heart
rhythm or beat called
arrhythmias

treat heart attacks, or
reduce your risk of heart
complications following a
heart attack
Atenolol GH may be either
used alone or in combination
with other medicines to treat
your condition.
Atenolol GH may also be
used in emergency situations
or during surgery to treat a
fast heart beat before, during
or after surgery.
Hypertension
Everyone has blood
pressure. This pressure helps
to push blood all around your
body. Your blood pressure
changes during the day,
depending on how busy you
are or how you are feeling.
You have hypertension (high
blood pressure) when your
blood pressure stays higher
than is needed, even when
you are calm and relaxed.
Regular blood pressure
checks

מאפייני מוצר

PI Atenolol GH v1 121024
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PRODUCT INFORMATION
ATENOLOL GH
Atenolol tablets
NAME OF THE MEDICINE
Atenolol.
CHEMICAL NAME:
2-[4-[(2_RS_)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]
acetamide.
MOLECULAR FORMULA: C
14
H
22
N
2
O
3
MOLECULAR WEIGHT: 266.3 g/mol
CAS REGISTRY NO.: 29122-68-7
DESCRIPTION
Atenolol is white to almost white powder. It is sparingly soluble in
water, soluble in ethanol, slightly soluble
in methylene chloride.
Atenolol GH is available as tablets containing 50 mg atenolol.
Atenolol GH tablets contain the following inactive ingredients:
starch-maize, gelatin, magnesium carbonate-
heavy, magnesium stearate and sodium lauryl sulfate
PHARMACOLOGY
Atenolol is a beta-adrenoreceptor blocking drugs which acts
preferentially on beta-receptors in the heart.
Selectivity decreases with increasing dose. It has little intrinsic
sympathomimetic activity and no membrane
stabilising activity.
Atenolol is a racemic mixture and its activity resides in the S(-)
enantiomer. It reduces raised blood pressure
by an unknown mechanism, and also inhibits exercise-induced
tachycardia and decreases plasma renin
concentration. It causes slight airways obstruction but less than that
seen with nonselective beta-blockers.
The inhibition of exercise-induced tachycardia is correlated with
blood levels but there is no correlation
between plasma concentrations and antihypertensive effect. Atenolol is
effective and well tolerated in
most ethnic populations although the response may be less in
Afro-Caribbean black patients.
The possible mechanism of the anti-anginal activity of atenolol
appears to be due to a reduction in left
ventricular work and oxygen utilisation resulting (mainly) from the
decrease in heart rate and contractility.
N
H
2
O
O
N
H
CH
3
CH
3
OH
and enantiomer
PI Atenolol GH v1 121024
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The antiarrhythmic effect of atenolol is apparently due to its
antisympathetic effect. There is no evidence
that membrane stabilising activity or intrinsic sympathomimetic
activity are necessary for antiarrhythmic
e