Land: Sydafrika
Språk: engelska
Källa: South African Health Products Regulatory Authority (SAHPRA)
Schering
INDICATIONS [/za_1143.html#1] [/za_1143.html#1] [/za_1143.html#1] CONTRA-INDICATIONS [/za_1143.html#1] [/za_1143.html#1] DOSAGE [/za_1143.html#1] [/za_1143.html#1] SIDE-EFFECTS [/za_1143.html#1] [/za_1143.html#1] [/za_1143.html#1] PREGNANCY [/za_1143.html#1] [/za_1143.html#1] OVERDOSE [/za_1143.html#1] IDENTIFICATION [/za_1143.html#1] [/za_1143.html#1] PATIENT INFORMATION GASTROGRAFIN SCHEDULING STATUS: S2 PROPRIETARY NAME (and dosage form): GASTROGRAFIN AQUEOUS SOLUTION FOR ENTERAL USE COMPOSITION Gastrografin contains a mixture of SODIUM AMIDOTRIZOATE and MEGLUMINE AMIDOTRIZOATE in a proportion of 10:66 (amidotrizoic acid or diatrizoic acid: 3,5-bis-acetamido-2,4,6-triiodobenzoic acid). 1 mL Gastrografin contains sodium amidotrizoate 100,00 mg and meglumine amidotrizoate 660,00 mg (sodium diatrizoate and meglumine diatrizoate) in aqueous solution plus flavourings and a wetting agent. Iodine concentration 370 mg/mL Iodine content per bottle of 100 mL 37 g Contrast medium concentration 760 mg/mL Contrast medium content per bottle of 100 mL 76 g Viscosity (mPa.s or cP) at 20°C 18,5 at 37°C 8,9 Osmotic pressure at 37°C (MPa) 5,58 (atm) 55,1 Osmolality at 37°C (osm/kg H 2 O) 2,15 PHARMACOLOGICAL CLASSIFICATION A. 28 Contrast media. PHARMACOLOGICAL ACTION ACTIONS The contrast-giving substances in Gastrografin are salts of amidotrizoic acid in which the X-ray absorbing iodine is present in stable chemical bond. PHARMACOKINETICS Following oral administration only about 3% of the amidotrizoic acid is absorbed from the stomach and intestines. This portion, and also any contrast medium that might Läs hela dokumentet