资料单张
CHEMMART GLICLAZIDE
TABLETS
_Contains the active ingredient gliclazide_
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
This leaflet answers some common
questions about gliclazide. It does not
contain all the available information.
It does not take the place of talking to
your doctor, pharmacist or diabetes
educator.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
this medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
You can also download the most up
to date leaflet from
www.apotex.com.au.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expect it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may want to read it again.
WHAT THIS MEDICINE IS
USED FOR
The name of your medicine is
Chemmart Gliclazide. It contains the
active ingredient gliclazide.
It is used to:
•
control blood glucose (sugar) in
patients with Type II diabetes
mellitus.
This type of diabetes is also known
as non-insulin-dependent diabetes
mellitus (NIDDM) or maturity onset
diabetes.
Gliclazide is used when diet and
exercise are not enough to control
your blood glucose.
Gliclazide can be used alone or
together with other medicines for
treating diabetes
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS_
Gliclazide belongs to a group of
medicines called the sulfonylureas.
Gliclazide lowers high blood glucose
by increasing the amount of insulin
produced by your pancreas.
Glucose is use
阅读完整的文件
产品特点
Product Information
– Australia
Chemmart Gliclazide Tablets
Page 1
CHEMMART GLICLAZIDE TABLETS
NAME OF THE MEDICINE
Gliclazide
Chemical Name:
1-(3-azabicyclo[3.3.0]oct-3-yl)-3-_p_-tolylsulphonylurea.
Structural Formula:
Molecular Formula:
C
15
H
21
N
3
O
3
S
Molecular Weight:
323.4
CAS Registry Number:
21187-98-4
DESCRIPTION
Gliclazide is a white or almost white powder which is practically insoluble in water.
Gliclazide tablets are intended for oral administration. Each tablet contains gliclazide 80 mg.
They are round, white, flat-sided tablets with bevelled e
dges, engraved “APO” over “80” on one side,
cross-scored on the other side.
In addition, each tablet contains the following inactive ingredients: croscarmellose sodium,
magnesium stearate,
colloidal anhydrous silica, lactose, microcrystalline cellulose
.
PHARMACOLOGY
PHARMACODYNAMICS
Gliclazide is a sulfonylurea hypoglycaemic agent which restores the diminished first-phase of insulin
secretion noted in non-insulin dependant diabetes mellitus. Gliclazide stimulates insulin secretion from
functional pancreatic
-cells and increases the sensitivity of the
-cells to a glucose stimulus (some
residual
-cell function is therefore necessary).
Any long-term hypoglycaemic activity of gliclazide is primarily due to its ability to maintain an effect on
insulin secretion, although extrapancreatic effects may also be involved. Extrapancreatic effects
demonstrated for gliclazide include improvement in insulin mediated glucose utilisation and potentiation of
postreceptor insulin sensiti
阅读完整的文件
资料单张 