Adenocor

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Adenosine

Available from:

Sanofi-Aventis Australia Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

ADENOCOR
®

_Adenosine_
CONSUMER MEDICINE INFORMATION (CMI)

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Adenocor.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you being given this
medicine against the benefits they
expect it will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
BEING GIVEN THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
WHAT ADENOCOR IS
USED FOR
Adenocor is a type of medicine used
to treat a condition called paroxysmal
supraventricular tachycardia
(including a condition called Wolff-
Parkinson-White syndrome). This is
when the heart beats too rapidly. If
left untreated this condition can be
life threatening.
Adenocor can also be used as an aid
to doctors, to understand how your
heart is working.
Adenocor works by slowing down
the electrical impulses which control
the heart rhythm. This allows the
heart rhythm to return to normal.
Adenocor is only given in hospitals.
It is given to you as an injection. The
effect of Adenocor only lasts for a
couple of minutes.
Your doctor, however, may prescribe
Adenocor for another purpose.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY IT HAS BEEN
PRESCRIBED FOR YOU.
This medicine is only available with
a doctor's prescription.
This medicine is not addictive.
BEFORE YOU ARE GIVEN IT
_WHEN YOU MUST NOT BE GIVEN_
_IT_
DO NOT RECEIVE ADENOCOR IF YOU
HAVE:
•
asthma or any other lung disease
•
recently had a heart transplant
•
some other problems with your
heart or heart rhythm
•
severe low blood pressure
DO NOT RECEIVE ADENOCOR IF YOU ARE
ALLERGIC TO IT OR ANY OF THE
INGREDIENTS LISTED AT THE END OF THIS
LEAFLET.
Some symptoms of an allergic
reaction include skin rash, itching,
shortness of breath or swelling of the
face, lips or tongue, which may cause
difficulty in swallowing or breathing.
_BEFORE YOU ARE GIVEN IT_
TELL YOUR DOCTOR IF YOU HAVE
ALLERGIES TO:
•
ANY

Summary of Product characteristics

Adenocor PIv3.0 CCDSv7 21 June 13 
Page 1  

PRODUCT INFORMATION 
ADENOCOR
®

NAME OF THE MEDICINE 
Adenocor (adenosine)  
Adenosine  is  designated  chemically  as  6-amino-9-ß-D-ribofuranosyl-9-H-purine  and  has  the 
following chemical structure: 

Adenosine is a white crystalline powder slightly soluble in water with a molecular weight of 267.2 
and an empirical formula of C
10
H
13
N
5
O
4
.   
DESCRIPTION 
Adenocor  is a sterile solution for  intravenous injection (rapid bolus), provided in clear glass vials.  
Each vial contains 6 mg of adenosine in 2 mL of a 0.9% w/v solution of sodium chloride in sterile 
water for injections. 
PHARMACOLOGY 
MECHANISM OF ACTION 
Adenocor  administered  by  rapid  intravenous  injections  depresses  conduction  through  the  AV 
node.    This  action  can  interrupt  re-entry  circuits  involving  the  AV  node  and  restore  normal  sinus 
rhythm in patients with paroxysmal supraventricular tachycardias and paroxysmal supraventricular 
tachycardias  associated  with  Wolff-Parkinson-White  Syndrome.    Once  the  circuit  has  been 
interrupted, the tachycardia stops and
normal sinus rhythm is re-established. 
By transiently slowing AV conduction, atrial activity is easier to evaluate from ECG recordings and 
therefore Adenocor can aid the diagnosis of broad
or narrow QRS complex tachycardias. 
Adenocor may be useful during electrophysiological studies to determine the site of AV block or to 
determine,  in  some  cases  of  pre-excitation,  whether  conduction  is  occurring  by  an  accessory 
pathway or via the AV node. 
HAEMODYNAMICS 
The usual intravenous bolus dose of 3 or 6 mg Adenocor usually has no systemic haemodynamic 
effects.  Rarely significant hypotension and tac