Страна: Австралія
мова: англійська
Джерело: Department of Health (Therapeutic Goods Administration)
Adenosine
Sanofi-Aventis Australia Pty Ltd
Medicine Registered
ADENOCOR ® _Adenosine_ CONSUMER MEDICINE INFORMATION (CMI) WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Adenocor. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you being given this medicine against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. WHAT ADENOCOR IS USED FOR Adenocor is a type of medicine used to treat a condition called paroxysmal supraventricular tachycardia (including a condition called Wolff- Parkinson-White syndrome). This is when the heart beats too rapidly. If left untreated this condition can be life threatening. Adenocor can also be used as an aid to doctors, to understand how your heart is working. Adenocor works by slowing down the electrical impulses which control the heart rhythm. This allows the heart rhythm to return to normal. Adenocor is only given in hospitals. It is given to you as an injection. The effect of Adenocor only lasts for a couple of minutes. Your doctor, however, may prescribe Adenocor for another purpose. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY IT HAS BEEN PRESCRIBED FOR YOU. This medicine is only available with a doctor's prescription. This medicine is not addictive. BEFORE YOU ARE GIVEN IT _WHEN YOU MUST NOT BE GIVEN_ _IT_ DO NOT RECEIVE ADENOCOR IF YOU HAVE: • asthma or any other lung disease • recently had a heart transplant • some other problems with your heart or heart rhythm • severe low blood pressure DO NOT RECEIVE ADENOCOR IF YOU ARE ALLERGIC TO IT OR ANY OF THE INGREDIENTS LISTED AT THE END OF THIS LEAFLET. Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing. _BEFORE YOU ARE GIVEN IT_ TELL YOUR DOCTOR IF YOU HAVE ALLERGIES TO: • ANY Прочитайте повний документ
Adenocor PIv3.0 CCDSv7 21 June 13 Page 1 PRODUCT INFORMATION ADENOCOR ® NAME OF THE MEDICINE Adenocor (adenosine) Adenosine is designated chemically as 6-amino-9-ß-D-ribofuranosyl-9-H-purine and has the following chemical structure: Adenosine is a white crystalline powder slightly soluble in water with a molecular weight of 267.2 and an empirical formula of C 10 H 13 N 5 O 4 . DESCRIPTION Adenocor is a sterile solution for intravenous injection (rapid bolus), provided in clear glass vials. Each vial contains 6 mg of adenosine in 2 mL of a 0.9% w/v solution of sodium chloride in sterile water for injections. PHARMACOLOGY MECHANISM OF ACTION Adenocor administered by rapid intravenous injections depresses conduction through the AV node. This action can interrupt re-entry circuits involving the AV node and restore normal sinus rhythm in patients with paroxysmal supraventricular tachycardias and paroxysmal supraventricular tachycardias associated with Wolff-Parkinson-White Syndrome. Once the circuit has been interrupted, the tachycardia stops and normal sinus rhythm is re-established. By transiently slowing AV conduction, atrial activity is easier to evaluate from ECG recordings and therefore Adenocor can aid the diagnosis of broad or narrow QRS complex tachycardias. Adenocor may be useful during electrophysiological studies to determine the site of AV block or to determine, in some cases of pre-excitation, whether conduction is occurring by an accessory pathway or via the AV node. HAEMODYNAMICS The usual intravenous bolus dose of 3 or 6 mg Adenocor usually has no systemic haemodynamic effects. Rarely significant hypotension and tac Прочитайте повний документ