资料单张
ADENOCOR
®
_Adenosine_
CONSUMER MEDICINE INFORMATION (CMI)
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Adenocor.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you being given this
medicine against the benefits they
expect it will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
BEING GIVEN THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
WHAT ADENOCOR IS
USED FOR
Adenocor is a type of medicine used
to treat a condition called paroxysmal
supraventricular tachycardia
(including a condition called Wolff-
Parkinson-White syndrome). This is
when the heart beats too rapidly. If
left untreated this condition can be
life threatening.
Adenocor can also be used as an aid
to doctors, to understand how your
heart is working.
Adenocor works by slowing down
the electrical impulses which control
the heart rhythm. This allows the
heart rhythm to return to normal.
Adenocor is only given in hospitals.
It is given to you as an injection. The
effect of Adenocor only lasts for a
couple of minutes.
Your doctor, however, may prescribe
Adenocor for another purpose.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY IT HAS BEEN
PRESCRIBED FOR YOU.
This medicine is only available with
a doctor's prescription.
This medicine is not addictive.
BEFORE YOU ARE GIVEN IT
_WHEN YOU MUST NOT BE GIVEN_
_IT_
DO NOT RECEIVE ADENOCOR IF YOU
HAVE:
•
asthma or any other lung disease
•
recently had a heart transplant
•
some other problems with your
heart or heart rhythm
•
severe low blood pressure
DO NOT RECEIVE ADENOCOR IF YOU ARE
ALLERGIC TO IT OR ANY OF THE
INGREDIENTS LISTED AT THE END OF THIS
LEAFLET.
Some symptoms of an allergic
reaction include skin rash, itching,
shortness of breath or swelling of the
face, lips or tongue, which may cause
difficulty in swallowing or breathing.
_BEFORE YOU ARE GIVEN IT_
TELL YOUR DOCTOR IF YOU HAVE
ALLERGIES TO:
•
ANY
阅读完整的文件
产品特点
Adenocor PIv3.0 CCDSv7 21 June 13
Page 1
PRODUCT INFORMATION
ADENOCOR
®
NAME OF THE MEDICINE
Adenocor (adenosine)
Adenosine is designated chemically as 6-amino-9-ß-D-ribofuranosyl-9-H-purine and has the
following chemical structure:
Adenosine is a white crystalline powder slightly soluble in water with a molecular weight of 267.2
and an empirical formula of C
10
H
13
N
5
O
4
.
DESCRIPTION
Adenocor is a sterile solution for intravenous injection (rapid bolus), provided in clear glass vials.
Each vial contains 6 mg of adenosine in 2 mL of a 0.9% w/v solution of sodium chloride in sterile
water for injections.
PHARMACOLOGY
MECHANISM OF ACTION
Adenocor administered by rapid intravenous injections depresses conduction through the AV
node. This action can interrupt re-entry circuits involving the AV node and restore normal sinus
rhythm in patients with paroxysmal supraventricular tachycardias and paroxysmal supraventricular
tachycardias associated with Wolff-Parkinson-White Syndrome. Once the circuit has been
interrupted, the tachycardia stops and
normal sinus rhythm is re-established.
By transiently slowing AV conduction, atrial activity is easier to evaluate from ECG recordings and
therefore Adenocor can aid the diagnosis of broad
or narrow QRS complex tachycardias.
Adenocor may be useful during electrophysiological studies to determine the site of AV block or to
determine, in some cases of pre-excitation, whether conduction is occurring by an accessory
pathway or via the AV node.
HAEMODYNAMICS
The usual intravenous bolus dose of 3 or 6 mg Adenocor usually has no systemic haemodynamic
effects. Rarely significant hypotension and tac
阅读完整的文件